Nutritional deficiencies in autoimmunity

Nutrition and autoimmunity share a bidirectional relationship: deficiencies can contribute to autoimmune disease development, while autoimmunity can impair nutrient absorption, leading to further deficiencies.

Nutritional deficiencies, particularly in essential micronutrients like iron, iodine, and folate (vitamin B9), are widespread, affecting about two billion people globally. These deficiencies are especially common among women, young children, and those with chronic health conditions, including digestive, hypothyroidism and autoimmune diseases.

Nutrition and autoimmunity share a bidirectional relationship: deficiencies can contribute to autoimmune disease development, while autoimmunity can impair nutrient absorption, leading to further deficiencies. Addressing both causes and consequences is essential for effective for addressing symptoms and this is where nutritional therapy plays a crucial role.

Personalised Nutrition for Vitamin & Mineral Deficiencies

Nutritional therapy focuses on identifying and addressing common vitamin and mineral deficiencies through intake assessments, consultations, and lab testing. This holistic approach allows us to determine why deficiencies occur and develop tailored solutions to correct them.

Common deficiencies associated with chronic health conditions include:

  • Iron – essential for oxygen transport and energy production.

  • Folate (B9) – crucial for DNA synthesis and cell growth.

  • Iodine – necessary for thyroid hormone production.

  • Vitamin B12 – supports nerve function and red blood cell production.

  • Vitamin D – regulates immune function and bone health.

Other important nutrients include vitamin A, B2, C, selenium, and magnesium, all of which support immune health and metabolic processes.

Nutrient Deficiencies in Autoimmune Diseases

If you have an autoimmune disease like Hashimoto’s thyroiditis, rheumatoid arthritis (RA), or multiple sclerosis (MS), nutrient deficiencies could be contributing to your symptoms. Even with treatment, many people continue to experience fatigue, pain, and other issues due to undiagnosed deficiencies.

Autoimmune Diseases as a Cause of Nutritional Deficiencies

Certain autoimmune conditions directly impair digestion and nutrient absorption. For example:

  • Celiac disease damages the small intestine, leading to deficiencies in B12, D, folate, iron, calcium, and zinc.

  • Inflammatory bowel disease (IBD) affects the GI tract, with Crohn’s disease patients particularly prone to iron, vitamin D, and B-vitamin deficiencies.

  • Multiple sclerosis (MS) may impact vitamin D metabolism, a critical nutrient for immune regulation.

Nutrient Deficiencies as a Risk Factor for Autoimmune Disease

Deficiencies may also increase the risk of developing autoimmunity. Key contributing factors include:

  1. Genetics – some individuals have genes affecting nutrient absorption and nutrient metabolism.

  2. Leaky gut – a compromised intestinal barrier allows toxins to enter the bloodstream, triggering immune responses.

  3. Environmental factors – poor diet, low sun exposure, lifestyle and toxins can increase autoimmune risk.

For instance, vitamin D deficiency is linked to higher rates of MS, Hashimoto’s, and RA. Symptoms include fatigue, muscle pain, and depression. Similarly, iodine deficiency is the leading cause of hypothyroidism worldwide, though excessive iodine intake can also be problematic for Hashimoto’s patients.

Other Causes & Consequences of Poor Nutrition

Beyond deficiencies, poor nutrition can contribute to intestinal permeability (leaky gut), a known trigger for autoimmunity. Factors that may impact nutrient status include:

  • Long-term medication use (e.g., antacids, which interfere with absorption)

  • Diets high in processed foods or low in essential nutrients

  • Restrictive eating habits (e.g., plant-based diets lacking B12, iron, and zinc)

  • Poorly planned gluten-free diets (such as diets that included many processed GF foods)

  • Sun avoidance (leading to vitamin D deficiency)

Addressing these issues is critical for restoring balance and supporting immune health.

How to Address Nutritional Deficiencies

Functional lab testing provides valuable insights into nutrient status, digestion, and overall health. Common tests include:

  • Iodine urine tests – to assess iodine level.

  • Stool tests – for gut health and absorption markers.

  • Urine tests- for metabolism, gut flora imbalances, toxin overload and vitamin B deficiencies.

  • Blood tests – for iron, folate, vitamin D, B12, and more.

  • Genetic tests- to assess genetic susceptibility.

Take Control of Your Nutritional Health

If you suspect a nutrient deficiency, we can help. Through personalised nutritional therapy, and with help of tests, we can uncover the root causes of your symptoms and create an effective plan for address them. Book a free 15-minute discovery call with one of our practitioners to get started.

Medical Disclaimer

The information provided is for educational purposes only and is not intended as medical advice. It should not be used to diagnose, treat, cure, or prevent any medical condition. Always consult with a qualified healthcare professional or nutrition practitioner before making any dietary changes or starting any supplementation. Individual needs vary, and professional guidance ensures safe and appropriate recommendations based on your personal health status.

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